Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

Morton, A.M. and Garside, P. and Mowat, A.M. and Harnett, M.M. (2008) Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo. Immunology, 125 (S1). p. 27. ISSN 0019-2805 (http://dx.doi.org/10.1111/j.1365-2567.2008.02974.x)

Abstract

T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.

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  Item type:	Article
  ID code:	19301
  Dates:	Date Event December 2008 Published
  Keywords:	ERK MAPK, in vitro, in vivo, T-cells, Immunology, Biology, Immunology, Immunology and Allergy
  Subjects:	Science > Microbiology > Immunology Science > Natural history > Biology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	18 May 2010 13:36
  Last modified:	18 Jan 2023 08:55
  URI:	https://strathprints.strath.ac.uk/id/eprint/19301