Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo

Morton, A.M. and Garside, P. and Mowat, A.M. and Harnett, M.M. (2008) Analysing the role of ERK MAPK signalling and potential downstream cell cycle modulators in tolerance and priming of antigen-specific cd4(+) T-cells in vitro and in vivo. Immunology, 125 (S1). p. 27. ISSN 0019-2805

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Official URL: http://dx.doi.org/10.1111/j.1365-2567.2008.02974.x

Abstract

T-cell recognition of Ag can result in priming or tolerance depending on the context in which Ag is recognised. We have previously shown that both qualitative and quantitative differences in T-cell signalling underlie the differential outcomes of priming and tolerance of antigenspecific T-cells.

Item type:	Article
ID code:	19301
Keywords:	ERK MAPK, in vitro, in vivo, T-cells, Immunology, Biology, Immunology, Immunology and Allergy
Subjects:	Science > Microbiology > Immunology Science > Natural history > Biology
Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Depositing user:	Strathprints Administrator
Date deposited:	18 May 2010 13:36
Last modified:	22 Oct 2017 00:07
URI:	https://strathprints.strath.ac.uk/id/eprint/19301
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