Can blood flow in the bone be measured using coloured labelled Microspheres?

Ghazzawi, H. and Abouel-Enin, S. and Reichert, I. and Gourlay, T. (2009) Can blood flow in the bone be measured using coloured labelled Microspheres? Internet Journal of Laboratory Medicine, 3 (2). ISSN 1937-8181

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Abstract

This study was designed to determine whether coloured micro-spheres represent a realistic alternative to more conventional techniques for the assessment of bone blood flow (BBF). BBF is normally measured using radioactive labelled micro-spheres, a technique that is accurate, but becoming increasingly challenged for safety and environmental reasons. Coloured micro-spheres come in two varieties, dye-fixed and dye eluting, and both have been employed for the measurement of blood flow in soft tissue for some time. However, measuring blood flow in bone presents a different challenge to that of soft tissue, insofar as the bone has to be dissolved using harsh chemicals to enable the harvesting of the micro-spheres for counting. This study therefore was designed to determine whether these micro-spheres would survive the harvesting process, and whether they could be identified and counted afterwards.

Author(s):Ghazzawi, H., Abouel-Enin, S., Reichert, I. and Gourlay, T.
Item type:Article
ID code:18712
Keywords:microspheres, blood flow, medicine, Bioengineering, Medicine (General), Engineering (General). Civil engineering (General)
Subjects:Technology > Engineering (General). Civil engineering (General) > Bioengineering
Medicine > Medicine (General)
Technology > Engineering (General). Civil engineering (General)
Department:Faculty of Engineering > Bioengineering
Depositing user: Ms Ashley Urie
Date deposited:13 Apr 2010 11:45
Last modified:31 Oct 2019 02:52
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URI:https://strathprints.strath.ac.uk/id/eprint/18712
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