Structural instability in an autophosphorylating kinase switch

Grinfeld, M. and Webb, S.D. (2009) Structural instability in an autophosphorylating kinase switch. Mathematical Biosciences, 219 (2). pp. 92-96. ISSN 0025-5564 (https://doi.org/10.1016/j.mbs.2009.02.005)

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Abstract

We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and show analytically that the property of being bistable is not necessarily conserved when degradation and synthesis of the kinase are taken into account.

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• Item metadata

  Item type:	Article
  ID code:	13399
  Dates:	Date Event June 2009 Published
  Subjects:	Science > Mathematics > Probabilities. Mathematical statistics Science > Mathematics
  Department:	Faculty of Science > Mathematics and Statistics
  Depositing user:	Mrs Carolynne Westwood
  Date deposited:	12 Nov 2009 15:03
  Last modified:	11 Nov 2024 09:09
  URI:	https://strathprints.strath.ac.uk/id/eprint/13399