A new drug vehicle - lipid coated biodegradable nanoparticles

Schäfer, J. and Sitterberg, Johannes and Ehrhardt, C. and Kumar, M.N.V. Ravi and Bakowsky, Udo (2008) A new drug vehicle - lipid coated biodegradable nanoparticles. Advances in Science and Technology, 57. pp. 148-153. ISSN 1662-8969

Abstract

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.

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• Item metadata

  Item type:	Article
  ID code:	12925
  Dates:	Date Event September 2008 Published
  Keywords:	atomic force microscopy, biodegradable nanoparticles, lipid coating, PLGA, Pharmacy and materia medica, Microbiology
  Subjects:	Medicine > Pharmacy and materia medica Science > Microbiology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Mr Scott Kilgariff
  Date deposited:	21 Aug 2009 12:58
  Last modified:	11 Nov 2021 01:53
  URI:	https://strathprints.strath.ac.uk/id/eprint/12925