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Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods

Ho, G. and Grant, M.H. and Barbenel, J.C. (2002) Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods. European Cells and Materials, 4 (2). pp. 55-56. ISSN 1473-2262

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Abstract

With the rapid development of tissue engineering and gene therapy, collagen-based biomaterials are frequently used as cell transplant devices; an example is bio-artificial skin substitutes [1-3]. In this study, we determined the effects of two different cell-seeding methods, monolayer and suspension seeding, on the rate of contraction of free-floating collagen and collagenglycosaminoglycan (GAG) gel matrices in vitro. 3T3 mouse fibroblasts were cultured in/on the matrices for up to 7 days.

Item type: Article
ID code: 6781
Keywords: tissue engineering, gene therapy, materials science, boengineering, cells, Bioengineering, Medicine (General), Human anatomy
Subjects: Technology > Engineering (General). Civil engineering (General) > Bioengineering
Medicine > Medicine (General)
Science > Human anatomy
Department: Faculty of Engineering > Bioengineering
Unknown Department
Faculty of Engineering > Electronic and Electrical Engineering
Related URLs:
Depositing user: Strathprints Administrator
Date Deposited: 29 Aug 2008
Last modified: 12 Mar 2012 10:45
URI: http://strathprints.strath.ac.uk/id/eprint/6781

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