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Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

McKeown, D. and McHugh, C.J. and McCabe, A. and Smith, W.E. and Graham, D. (2002) Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine. Heterocycles, 57 (7). pp. 1227-1230. ISSN 0385-5414

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Abstract

The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

Item type: Article
ID code: 1065
Keywords: benzotriazole, chemistry, organic, Chemistry, Organic Chemistry, Analytical Chemistry, Pharmacology
Subjects: Science > Chemistry
Department: Faculty of Science > Pure and Applied Chemistry
Related URLs:
    Depositing user: Mr Derek Boyle
    Date Deposited: 16 May 2006
    Last modified: 04 Sep 2014 11:23
    URI: http://strathprints.strath.ac.uk/id/eprint/1065

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