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Rapid assembly of highly-functionalised difluorinated cyclooctenones via ring-closing metathesis

Kariuki, Benson M. and Owton, W. Martin and Percy, Jonathan and Pintat, Stephane and Smith, Clive A. and Spencer, Neil S and Thomas, Andrew C and Watson, Martin (2002) Rapid assembly of highly-functionalised difluorinated cyclooctenones via ring-closing metathesis. Chemical Communications, 2002 (3). pp. 228-229. ISSN 1359-7345

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Building block methodology from trifluoroethanol and ringclosing metathesis using a Fürstner modification of Grubbs’ conditions allows the rapid synthesis of novel difluorinated cyclooctenones.