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Antimicrobial constituents from the stem bark of feronia limonia

Rahman, M.M. and Gray, A. (2002) Antimicrobial constituents from the stem bark of feronia limonia. Phytochemistry, 59. pp. 73-77. ISSN 0031-9422

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The stem bark of Feronia limonia (Fam. Rutaceae) yielded (−)-(2S)-5,3′-dihydroxy-4′-methoxy-6″,6″-dimethylchromeno-(7,8,2″,3″)-flavanone along with several known compounds including an alkaloid, five coumarins, a flavanone, a lignan, three sterols and a triterpene. The structures of these compounds were determined by spectroscopic methods, mainly 1D and 2D NMR. The antimicrobial screening of compounds by a microdilution technique resulted in MICs in the range 25–100 μg/ml. Other biological activities of the known compounds are also discussed.