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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Effects of substituting Fructose by Mannitol in a pharmaceutical formulation

Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573

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Abstract

Pharmaceutical formulations can increase the solubility and stability of drug molecules. L-p-10 Boronphenylalanine (BPA) has previously been formulated with Fructose. Here we present a novel BPA formulation with Mannitol resulting in improved kinetic solubility along with the removal of possible Fructose related intolerance reactions.