Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573Full text not available in this repository. (Request a copy from the Strathclyde author)
Pharmaceutical formulations can increase the solubility and stability of drug molecules. L-p-10 Boronphenylalanine (BPA) has previously been formulated with Fructose. Here we present a novel BPA formulation with Mannitol resulting in improved kinetic solubility along with the removal of possible Fructose related intolerance reactions.
|Keywords:||P-boronophenylalanine, complex-formation, monosaccharides, solubility, Pharmacy and materia medica, Pharmaceutical Science, Pharmacology|
|Subjects:||Medicine > Pharmacy and materia medica|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||24 Jun 2011 10:48|
|Last modified:||04 May 2016 18:41|