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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S. S199. ISSN 0378-4274

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Abstract

Cobalt chromium (Co-Cr) alloy metal-on-metal (MOM) hip resurfacing has become increasingly common in younger, more active patients. However, there is growing concern regarding levels of Co-Cr wear debris and ions released. Using the rodent air pouch model, described as a facsimile synovium, we assessed the inflammatory response to artificially generated Co-Cr wear debris.