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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Impact of varying intensities of blue-light exposure on 3T3 cells

Smith, S. and Maclean, M. and MacGregor, S.J. and Anderson, J.G. and Grant, M.H. (2009) Impact of varying intensities of blue-light exposure on 3T3 cells. European Cells and Materials, 18 (Suppl.). p. 106. ISSN 1473-2262

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Abstract

There is the need to develop a compatible sterilisation method for hybrid biomaterials. High-intensity blue light in the 405 nm region has been shown to be an effective bacterial decontamination method [1], to cause no noticeable damage to the gross structure of type-I collagen monomer (when treated at 10 mW/cm2) [2], and to have no noticeable effect on 3T3 cell viability, growth rate, redox state or lactate dehydrogenase (LDH) leakage (at 1.0 mW/cm2) [2]. The purpose of this research was to investigate the effect of varying the blue-light intensity on the 3T3 cell response parameters.