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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts

Saddiq, Z.A. and Barbenel, J.C. and Grant, M.H. (2005) The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts. In: Tissue and Cell Engineering Society Meeting, 2005-05-20 - 2005-05-22.

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Abstract

Collagen based scaffolds are widely used for tissue engineering strategies; many are designed to biodegrade gradually and become populated with host cells. The effect of infiltration by host cells on the mechanical properties of the scaffolds is unclear. We have used fibroblast populated collagen lattices to study the effects of the presence of 3T3 mouse fibroblasts on the mechanical properties of collagen gels containing glycosaminoglycans (GAGs) crosslinked with the carbodiimide, 1,1-carbonyldiimidazole (CDI), and the polyamine, putrescine (Put).