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The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts

Saddiq, Z.A. and Barbenel, J.C. and Grant, M.H. (2005) The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts. In: Tissue and Cell Engineering Society Meeting, 2005-05-20 - 2005-05-22, London, England.

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Abstract

Collagen based scaffolds are widely used for tissue engineering strategies; many are designed to biodegrade gradually and become populated with host cells. The effect of infiltration by host cells on the mechanical properties of the scaffolds is unclear. We have used fibroblast populated collagen lattices to study the effects of the presence of 3T3 mouse fibroblasts on the mechanical properties of collagen gels containing glycosaminoglycans (GAGs) crosslinked with the carbodiimide, 1,1-carbonyldiimidazole (CDI), and the polyamine, putrescine (Put).

Item type: Conference or Workshop Item (Paper)
ID code: 8437
Notes: Also published in: 1. Journal of Biomedical Materials Research Part A (2008), 89A(3), pp697-706. 2. European Cells and Materials (2005), 10(S2), p64. (This is a variant record)
Keywords: mechanical engineering, collagen gels, glycosaminoglycans, fibroblasts, crosslinked collagen, fibroblast populated collagen gels, collagen/glycosaminoglycan gels, Bioengineering
Subjects: Technology > Engineering (General). Civil engineering (General) > Bioengineering
Department: Faculty of Engineering > Bioengineering
Unknown Department
Faculty of Engineering > Electronic and Electrical Engineering
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Depositing user: Strathprints Administrator
Date Deposited: 30 Jul 2009 13:16
Last modified: 04 Oct 2012 17:17
URI: http://strathprints.strath.ac.uk/id/eprint/8437

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