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World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts

Ganguli, A. and Lloyd, A.W. and Meikle, S.T. and Grant, M.H. (2001) The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. In: Transactions of the 25th Annual Meeting of the Society for Biomaterials. Society for Biomaterials. ISBN 8024572001

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Abstract

Coating of the hydroxyapatite (HA) ceramic component of artificial hip joints with the bisphosphonates clodronate (C) and pamidronate (P) has been proposed as a means to minimise osteolysis and thereby prevent loosening of the implant. However, the effect of the bisphosphonate coating on bacterial adhesion to the HA materials must be determined before this approach can be implemented.