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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Study of bovine articular chondrocytes on thin film polycaprolactone surfaces

Angeli, F. and Connolly, P. (2002) Study of bovine articular chondrocytes on thin film polycaprolactone surfaces. European Cells and Materials, 4 (2). p. 80. ISSN 1473-2262

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Abstract

In tissue engineering significant progress has been made in the development of biodegradable polymer scaffolds for tissue culture (see [1] for review). Applications for tissue growth and replacement using donor or animal cells are under investigation for a range of tissue types including; cardiac cells, neural tissue, tendon, bone and cartilage. A number of factors are important in achieving successfully engineered tissue such as; polymer type, surface chemistry, oxygenation, nutrient delivery and expression of extracellular proteins. It has also been shown in the field of microchip-cell devices that microstructure is critical to growth and alignment of many cell types.