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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Pharmacy-implemented guidelines on switching from intravenous to oral antibiotics: an intervention study

McLaughlin, C.M. and Bodasing, N. and Boyter, A.C. and Fenelon, C. and Fox, J.G. and Seaton, A.V. (2005) Pharmacy-implemented guidelines on switching from intravenous to oral antibiotics: an intervention study. Quarterly Journal of Medicine, 98 (10). pp. 745-752. ISSN 1460-2725

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Abstract

A high proportion of medical in-patients in the UK receive intravenous (IV) antibiotic therapy. This may be inappropriate in non-severe infections, or unnecessarily prolonged. Data relating to infection and antibiotic therapy were collected for 4 weeks pre-intervention (group 1) and 4 weeks post intervention (group 2). Six months later, data were collected for a further 4 weeks following a second intervention (group 3). Interventions consisted of pharmacy-led implementation of guidelines incorporating criteria for IV therapy and switching to the oral route. The second intervention also included pharmacy-initiated feedback on prescribing. The main outcome measures were IV antibiotic duration, and appropriateness of the IV route and switching.