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Generating diversity in difluoromethyl ketone derivatives

DeBoos, Gareth A and Fullbrook, Jeremy J and Percy, Jonathan (2001) Generating diversity in difluoromethyl ketone derivatives. Organic Letters, 3 (18). pp. 2859-2861. ISSN 1523-7060

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Two consecutive palladium-catalyzed coupling reactions from a readily available difluoroenol stannane set the stage for the synthesis of a range of difluoro- and halodifluoromethyl ketones upon a variable aryl template.