Chappelle, Michael R. and Morgan, Alan D. and Tomkinson, Nicholas C. O. and Willson, Timothy M. (2001) Tritium labeling of the PXR ligand GW5801 - an unexpected tritium exchange reaction. In: Synthesis and applications of isotopically labelled compounds, volume 7. Wiley-Blackwell, pp. 80-83. ISBN 0471495018
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
H-T exchange on 4,3,5-HO(Me3C)2C6H2CHO in presence of Crabtree's catalyst gave exclusively 4,3,5-HO(Me3C)2C6H2CTO, which was treated with CH2[P(O)(OEt)2]2 to give 4,3,5-HO(Me3C)2C6H2CT:CH[P(O)(OEt)2]2. The absence of ring tritiation in 4,3,5-HO(Me3C)2C6H2CHO is attributed to steric hindrance by the tert.-Bu groups. [on SciFinder(R)]
| Item type: | Book Section |
|---|---|
| ID code: | 36062 |
| Notes: | CAPLUS AN 2002:174743(Conference) 2nd ISBn print: 9780471495017 |
| Keywords: | tritium labeling, PXR ligand GW5801 , tritium exchange reaction, Chemistry |
| Subjects: | Science > Chemistry |
| Department: | Faculty of Science > Pure and Applied Chemistry |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 21 Nov 2011 16:37 |
| Last modified: | 04 Oct 2012 16:37 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/36062 |
Actions (login required)
| View Item |