Dougan, Jennifer A. and MacRae, Douglas and Graham, Duncan and Faulds, Karen (2011) DNA detection using enzymatic signal production and SERS. Chemical Communications (London), 47 (16). pp. 4649-4651. ISSN 0009-241XFull text not available in this repository. (Request a copy from the Strathclyde author)
A novel DNA assay is demonstrated which relies on the production of a surface enhanced resonance Raman scattering (SERS) signal following sequence specific hybridisation and enzyme hydrolysis. This method achieves high sensitivity and specificity that can be applied to the detection of unlabelled duplex DNA and is the first step towards a SERS based signal amplification approach.
|Keywords:||resonance ram-scattering, exonuclease, nanoparticles, fluorescence, lambda, TIC - Bionanotechnology, Physical and theoretical chemistry|
|Subjects:||Science > Chemistry > Physical and theoretical chemistry|
|Department:||Faculty of Science > Pure and Applied Chemistry|
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|Depositing user:||Pure Administrator|
|Date Deposited:||17 Oct 2011 14:42|
|Last modified:||12 Jun 2013 14:32|
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