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Presence of free radicals in intracameral agents commonly used during cataract surgery

Lockington, David and Macdonald, EC and Young, David and Stewart, P. and Caslake, Muriel and Ramaesh, Kanna (2010) Presence of free radicals in intracameral agents commonly used during cataract surgery. British Journal of Ophthalmology, 94 (12). pp. 1674-7.

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Abstract

Free radicals are known to cause cellular damage and are present in ophthalmic preparations. Corneal defence mechanisms are bypassed in intra-ocular surgery. We evaluated commonly used intracameral agents to ascertain the presence of free radicals and investigate the possibility of anterior segment and endothelial toxicity.