Lyons, R E and McLeod, R and Roberts, C W (2002) Toxoplasma gondii tachyzoite-bradyzoite interconversion. Trends in Parasitology, 18 (5). pp. 198-201. ISSN 1471-4922
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
During infection in the intermediate host, Toxoplasma gondii undergoes stage conversion between the rapidly dividing tachyzoite that is responsible for acute toxoplasmosis and the slowly replicating, encysted bradyzoite stage. This process of tachyzoite-bradyzoite interconversion is central to the pathogenesis and longevity of infection. Recent research has identified several stage-specific genes and proteins. However, despite recent advances in the understanding of Toxoplasma cell biology, more research is necessary to elucidate the complex events occurring during tachyzoite-bradyzoite interconversion. Here, a brief summary of this process is provided and a new method to characterize gene expression during interconversion is introduced.
| Item type: | Article |
|---|---|
| ID code: | 31731 |
| Keywords: | tissue cyst formation, molecular-cloning, stage converstion, differential expression, targeted disruption, gene, antigen, surface, induction, enzymes, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 13 Jul 2011 09:57 |
| Last modified: | 12 Mar 2012 11:28 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/31731 |
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