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A theoretical investigation of chirp insonification of ultrasound contrast agents

Barlow, Euan and Mulholland, Anthony J. and Gachagan, Anthony and Nordon, Alison (2011) A theoretical investigation of chirp insonification of ultrasound contrast agents. Ultrasonics, 51 (6). pp. 725-733. ISSN 0041-624X

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Abstract

A theoretical investigation of second harmonic imaging of an Ultrasound Contrast Agent (UCA) under chirp insonification is considered. By solving the UCA's dynamical equation analytically, the effect that the chirp signal parameters and the UCA shell parameters have on the amplitude of the second harmonic frequency are examined. This allows optimal parameter values to be identified which maximise the UCA's second harmonic response. A relationship is found for the chirp parameters which ensures that a signal can be designed to resonate a UCA for a given set of shell parameters. It is also shown that the shell thickness, shell viscosity and shell elasticity parameter should be as small as realistically possible in order to maximise the second harmonic amplitude. Keller-Herring, Second Harmonic, Chirp, Ultrasound Contrast Agent.

Item type: Article
ID code: 31334
Keywords: keller–herring, ultrasound contrast agent, second harmonic , chirp, Probabilities. Mathematical statistics, Electrical engineering. Electronics Nuclear engineering, Chemistry, Acoustics and Ultrasonics
Subjects: Science > Mathematics > Probabilities. Mathematical statistics
Technology > Electrical engineering. Electronics Nuclear engineering
Science > Chemistry
Department: Faculty of Science > Mathematics and Statistics
Faculty of Engineering > Electronic and Electrical Engineering
Faculty of Science > Pure and Applied Chemistry
Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)
Related URLs:
Depositing user: Pure Administrator
Date Deposited: 23 May 2011 10:21
Last modified: 27 Mar 2014 09:22
URI: http://strathprints.strath.ac.uk/id/eprint/31334

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