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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Comparison of PAM and CEA as detectors of mammary micrometastases

Anderson, J.M. and Jhunjhunwala, S.K. and Ewan, J.M. and Stimson, W.H. and Gettinby, G. (1979) Comparison of PAM and CEA as detectors of mammary micrometastases. British Journal of Cancer, 40 (2). p. 320. ISSN 1532-1827

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Abstract

Nineteen of 61 Stage I or II mammary-cancer bearers developed conventionally detectable metastases within 8-44 (median 15) months of commencing follow-up. Serum pregnancy-associated macroglobulin (PAM, PAG, O2 PAG) rose by > 75% above baseline values before detection of metastases in all but 4 of these 19 patients and in 11/42 remaining well. The means of the maximum percentage rises in PAM were 286 for the metastatic and 67 for the well patients (P<0-01 in a Mann-Whitney U-test).