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Research under the microscope...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model

Mairs, R.J. and Wideman, C.L. and Angerson, W.J. and Whateley, T.L. and Reza, M.S. and Reeves, J.R. and Robertson, L.M. and Neshasteh-Riz, A. (2000) Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model. British Journal of Cancer, 82 (1). pp. 74-80. ISSN 0007-0920

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Abstract

As part of an NHS Executive Trent regional initiative we considered the role and cost-effectiveness of high dose chemotherapy in the treatment of relapsed Hodgkin's disease and non-Hodgkin's lymphoma. The key trials and case series show an additional patient benefit of 0.8-1.1 life years over standard chemotherapy. We estimate incremental cost per life year gained of £12 800-£17 600, which reduces further if long-term benefits are considered. High dose chemotherapy in these conditions is both life-saving and cost-effective.