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Theoretical analysis of chirp excitation of contrast agents

Barlow, E. and Mulholland, A. and Gachagan, A. and Nordon, A. (2009) Theoretical analysis of chirp excitation of contrast agents. Physics Procedia, 3 (1). pp. 743-747. ISSN 1875-3892

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Analytic expressions are found for the amplitude of the first and second harmonics of the Ultrasound Contrast Agent's (UCA's) dynamics when excited by a chirp. The dependency of the second harmonic amplitude on the system parameters, the UCA shell parameters, and the insonifying signal parameters is then investigated. It is shown that optimal parameter values exist which give rise to a clear increase in the second harmonic component of the UCA's motion.