Picture of scraped petri dish

Scrape below the surface of Strathprints...

Explore world class Open Access research by researchers at the University of Strathclyde, a leading technological university.

Explore

The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

Ferro, V.A. and Habeeb, F. and Stables, Graham and Bradbury, F. and nong, S. and Cameron, P. and Plevin, R.J. (2007) The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods, 42 (4). pp. 388-393. ISSN 1046-2023

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.