Carbohydrate-active enzymes (CAZymes) and woody/herbaceous host preference in pectobacteriaceae

Tools

Hobbs, Emma E. M. and Gloster, Tracey M. and Pritchard, Leighton (2024) Carbohydrate-active enzymes (CAZymes) and woody/herbaceous host preference in pectobacteriaceae. In: ICPPB & Biocontrol 2024, 2024-07-07 - 2024-07-12, Virginia Tech.

[thumbnail of Hobbs-etal-ICPPB-2025-Carbohydrate-active-enzymes-CAZymes-and-woody-herbaceous]
Preview
 Text. Filename: Hobbs-etal-ICPPB-2025-Carbohydrate-active-enzymes-CAZymes-and-woody-herbaceous.pdf
Final Published Version
License: Creative Commons Attribution 4.0 logo
Download (8MB)| Preview

Abstract

Lignocellulose is a globally abundant, renewable carbon source with promise for fossil fuel replacement in energy generation and as feedstock for sythetic processes. Industrial conversion of lignocellulosic biomass is currently ineffcient. Pectobacteriaceae are plant pathogens that break down host plant material using carbohydrate-active enzyme (CAZyme) mixtures that act in concert. Pilot studies show these enzymes have potential to improve biofuel production effciency. Lignocelluosic biomass composition is highly varied. Design of effective CAZyme mixtures for lignocellulose degradation is diffcult. Only a minority of CAZymes have so far been characterised. Practical screens of CAZymes (an organism’s CAZome) can be slow and resource-intensive. Bioinformatic analysis of microbial genomes may help accelerate design of industrially useful CAZyme mixtures. We mined CAZomes across the Pectobacteriaceae to identify co-evolved CAZyme mixtures, gaining potential insight into the host adaptation of these pathogens, using the cazomevolve software package.

ORCID iDs

Hobbs, Emma E. M., Gloster, Tracey M. and Pritchard, Leighton ORCID logoORCID: https://orcid.org/0000-0002-8392-2822;
CORE (COnnecting REpositories)