Targeting radiotherapy to cancer by gene transfer

Mairs, R. J. and Boyd, M. (2003) Targeting radiotherapy to cancer by gene transfer. Journal of Biomedicine and Biotechnology, 2003 (2). pp. 102-109. ISSN 1110-7243 (https://doi.org/10.1155/S1110724303209062)

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Abstract

Targeted radionuclide therapy is an alternative method of radiation treatment which uses a tumor-seeking agent carrying a radioactive atom to deposits of tumor, wherever in the body they may be located. Recent experimental data signifies promise for the amalgamation of gene transfer with radionuclide targeting. This review encompasses aspects of the integration of gene manipulation and targeted radiotherapy, highlighting the possibilities of gene transfer to assist the targeting of cancer with low molecular weight radiopharmaceuticals.

ORCID iDs

Mairs, R. J. and Boyd, M. ORCID logoORCID: https://orcid.org/0000-0003-4120-2218;