Evaluation of risk factors for postbooster Omicron COVID-19 deaths in England

Nafilyan, Vahé and Ward, Isobel L. and Robertson, Chris and Sheikh, Aziz, National Core Studies—Immunology Breakthrough Consortium (2022) Evaluation of risk factors for postbooster Omicron COVID-19 deaths in England. JAMA Network Open, 5 (9). e2233446. ISSN 2574-3805 (https://doi.org/10.1001/jamanetworkopen.2022.33446)

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Abstract

With the emergence of the Omicron variant, it has become critical to identify risk factors associated with COVID-19 death in individuals who have completed primary vaccination and received a messenger RNA (mRNA) booster dose. Existing evidence is based on people who have received 1 or 2 doses of a COVID-19 vaccine and were infected by the Alpha or Delta variant.1-3 Understanding which groups are at increased risk of COVID-19 death after receiving a booster is crucial for the prioritization of further booster doses and access to COVID-19 therapeutics.