Evaluating intervention strategies in controlling COVID-19 spread in care homes : an agent-based model

Nguyen, Le Khanh Ngan and Howick, Susan and McLafferty, Dennis and Anderson, Gillian Hopkins and Pravinkumar, Josephine and Van Der Meer, Robert and Megiddo, Itamar (2020) Evaluating intervention strategies in controlling COVID-19 spread in care homes : an agent-based model. Infection Control and Hospital Epidemiology. ISSN 0899-823X (https://doi.org/10.1017/ice.2020.1369)

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Background: Care homes are vulnerable to widespread transmission of COVID-19 with poor outcomes for staff and residents. Infection control interventions in care homes need to not only be effective in containing the spread of COVID-19 but also feasible to implement in this special setting which is both a healthcare institution and a home. Methods: We developed an agent-based model that simulates the transmission dynamics of COVID-19 via contacts between individuals, including residents, staff members, and visitors in a care home setting. We explored a representative care home in Scotland in our base case and explore other care home setups in an uncertainty analysis. We evaluated the effectiveness of a range of intervention strategies in controlling the spread of COVID-19. Results: In the presence of the reference interventions that have been implemented in many care homes, including testing of new admissions, isolation of symptomatic residents, and restricted public visiting, routine testing of staff appears to be the most effective and practical approach. Routine testing of residents is no more effective as a reference strategy while routine testing of both staff and residents only shows a negligible additive effect. Modelling results are very sensitive to transmission probability per contact, but the qualitative finding is robust to varying parameter values in our uncertainty analysis. Conclusions: Our model predictions suggest that routine testing should target staff in care homes in conjunction with adherence to strict hand hygiene and using personal protective equipment to reduce risk of transmission per contact.


Nguyen, Le Khanh Ngan ORCID logoORCID: https://orcid.org/0000-0002-6742-6896, Howick, Susan ORCID logoORCID: https://orcid.org/0000-0002-0796-7981, McLafferty, Dennis, Anderson, Gillian Hopkins ORCID logoORCID: https://orcid.org/0000-0002-5768-6360, Pravinkumar, Josephine, Van Der Meer, Robert ORCID logoORCID: https://orcid.org/0000-0002-9442-1628 and Megiddo, Itamar ORCID logoORCID: https://orcid.org/0000-0001-8391-6660;