Design and numerical simulation for the development of an expandable paediatric heart valve

Kerr, Monica M. and Gourlay, Terence (2020) Design and numerical simulation for the development of an expandable paediatric heart valve. International Journal of Artificial Organs, 44 (7). pp. 518-524. ISSN 0391-3988 (https://doi.org/10.1177/0391398820977509)

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Abstract

Current paediatric valve replacement options cannot compensate for somatic growth, leading to an obstruction of flow as the child outgrows the prosthesis. This often necessitates an increase in revision surgeries, leading to legacy issues into adulthood. An expandable valve concept was modelled with an inverse relationship between annulus size and height, to retain the leaflet geometry without requiring additional intervention. Parametric design modelling was used to define certain valve parameter aspect ratios in relation to the base radius, Rb, including commissural radius, Rc, valve height, H and coaptation height, x. Fluid-structure simulations were subsequently carried out using the Immersed Boundary method to radially compress down the fully expanded aortic valve whilst subjecting it to diastolic and systolic loading cycles. Leaflet radial displacements were analysed to determine if valve performance is likely to be compromised following compression. Work is ongoing to optimise valvular parameter design for the paediatric patient cohort.

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