Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services

Akram, Gazala and Mitchell, Fiona (2019) Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services. BMJ Case Reports, 12 (6). e228509. ISSN 1757-790X

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    Abstract

    Second-generation antipsychotics are used to treat a variety of psychiatric symptoms and illnesses as well as the behavioural aspects of various neurodevelopmental disorders. However, there is reluctance in using second-generation long-acting injectable antipsychotics in child psychiatry services. We present a case of a 12-year-old child whose presentation and medication regime warranted the use of aripiprazole long-acting injection against a backdrop of potential CYP P450 enzyme interactions as a consequence of polypharmacy. The case also describes the difficulties encountered working across different health sectors and agencies and highlights the ongoing need for skills-based Continuous Professional Development for Child and Adolescent Mental Health Services-based nursing staff.

    ORCID iDs

    Akram, Gazala ORCID logoORCID: https://orcid.org/0000-0003-3207-8091 and Mitchell, Fiona;
    • Item type:Article
      ID code:69169
      Dates:
      Date
      Event
      14 June 2019
      Published
      3 June 2019
      Accepted
      Keywords:antipsychotics drugs, child psychiatry, polypharmacy, Pharmacy and materia medica, Medicine(all), Pharmacology, Toxicology and Pharmaceutics(all)
      Subjects:Medicine > Pharmacy and materia medica
      Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
      Depositing user: Pure Administrator
      Date deposited:01 Aug 2019 10:25
      Last modified:15 Aug 2021 01:38
      URI:https://strathprints.strath.ac.uk/id/eprint/69169
    CORE (COnnecting REpositories)