Deposition of elastic fibres in a murine cutaneous wound-healing model

Shuttleworth, L. and Black, R.A. and Ferguson, M. and Herrick, S. (2005) Deposition of elastic fibres in a murine cutaneous wound-healing model. International Journal of Experimental Pathology, 86 (3). A68-A68. ISSN 0959-9673

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Official URL: http://dx.doi.org/10.1111/j.0959-9673.2005.00426.x

Abstract

Abstract of paper from TCES (Tissue and Cell Engineering Society) meeting in 2005. The ability of the skin to extend and recoil is mediated by an elastic fibre network comprising elastin molecules deposited on a microfibrillar scaffold. Studies have demonstrated reduced tensile strength in scar tissue following cutaneous wounding, possibly due to decreased amounts of elastic fibres1. The dermal component of artificial skin substitutes also lacks an organised elastic fibre network, which may contribute to excessive contraction and scarring post-grafting. This study aimed to document the temporal and spatial distribution of elastic fibres following incisional and excisional cutaneous wounding in mice.

Item type:	Article
ID code:	6831
Keywords:	bioengineering, biotechnology, skin, fibre network, elastic fibres, Bioengineering, Cell Biology, Molecular Biology, Pathology and Forensic Medicine
Subjects:	Technology > Engineering (General). Civil engineering (General) > Bioengineering
Department:	Faculty of Engineering > Bioengineering
Depositing user:	Strathprints Administrator
Date deposited:	04 Sep 2008
Last modified:	22 Mar 2017 09:42
Related URLs:	http://www.ecmjournal.org/journal/supple... http://www.ecmjournal.org/journal/supple...
URI:	https://strathprints.strath.ac.uk/id/eprint/6831
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