Deposition of elastic fibres in a murine cutaneous wound-healing model
Shuttleworth, L. and Black, R.A. and Ferguson, M. and Herrick, S. (2005) Deposition of elastic fibres in a murine cutaneous wound-healing model. International Journal of Experimental Pathology, 86 (3). A68-A68. ISSN 0959-9673 (https://doi.org/10.1111/j.0959-9673.2005.00426.x)
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Abstract of paper from TCES (Tissue and Cell Engineering Society) meeting in 2005. The ability of the skin to extend and recoil is mediated by an elastic fibre network comprising elastin molecules deposited on a microfibrillar scaffold. Studies have demonstrated reduced tensile strength in scar tissue following cutaneous wounding, possibly due to decreased amounts of elastic fibres1. The dermal component of artificial skin substitutes also lacks an organised elastic fibre network, which may contribute to excessive contraction and scarring post-grafting. This study aimed to document the temporal and spatial distribution of elastic fibres following incisional and excisional cutaneous wounding in mice.
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Item type: Article ID code: 6831 Dates: DateEvent2005PublishedSubjects: Technology > Engineering (General). Civil engineering (General) > Bioengineering Department: Faculty of Engineering > Bioengineering Depositing user: Strathprints Administrator Date deposited: 04 Sep 2008 Last modified: 08 Apr 2024 15:56 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/6831