Modification of polymer surfaces: optimization of approaches

Courtney, J.M. and Zhao, X.B. and Qian, H. and Sharma, A. (2003) Modification of polymer surfaces: optimization of approaches. Perfusion, 18 (1). pp. 33-39. ISSN 0267-6591 (http://dx.doi.org/10.1191/0267659103pf633oa)

Abstract

Modification of polymer surfaces to achieve a surface with enhanced compatibility is an important means of obtaining improved biomaterials. Techniques are available for altering the hydrophilicity or charge of a surface, attaching macromolecules or attempting to resemble cell membranes. Relevant to the clinical success of a modified surface is the modification procedure and a procedure based on incorporation as opposed to surface treatment has potential advantages. The modification of plasticized vinyl chloride (PVC) by the incorporation of cyclodextrins is described. In comparison to unmodified PVC controls, cyclodextrin incorporation reduced fibrinogen adsorption, with the extent of reduction dependent on the type and quantity of cyclodextrin incorporated.

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  Item type:	Article
  ID code:	6795
  Dates:	Date Event 2003 Published
  Keywords:	polymers, perfusion, hydrophilicity, adsorption, bioengineering, Bioengineering, Health Professions (miscellaneous), Cardiology and Cardiovascular Medicine, Medicine (miscellaneous)
  Subjects:	Technology > Engineering (General). Civil engineering (General) > Bioengineering
  Department:	Faculty of Engineering > Bioengineering Unknown Department
  Depositing user:	Strathprints Administrator
  Date deposited:	01 Sep 2008
  Last modified:	07 Dec 2022 02:55
  URI:	https://strathprints.strath.ac.uk/id/eprint/6795