Concerted nucleophilic aromatic substitution reactions

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Rohrbach, Simon and Smith, Andrew J. and Pang, Jia Hao and Poole, Darren L. and Tuttle, Tell and Chiba, Shunsuke and Murphy, John A. (2019) Concerted nucleophilic aromatic substitution reactions. Angewandte Chemie International Edition, 58 (46). pp. 16368-16388. ISSN 1521-3773 (https://doi.org/10.1002/anie.201902216)

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Abstract

Recent developments in experimental and computational chemistry have identified a rapidly growing class of nucleophilic aromatic substitutions that proceed by concerted (cS NAr) rather than classical, two-step, S NAr mechanisms. Whereas traditional S NAr reactions require substantial activation of the aromatic ring by electron-withdrawing substituents, such activating groups are not mandatory in the concerted pathways.

ORCID iDs

Rohrbach, Simon, Smith, Andrew J. ORCID logoORCID: https://orcid.org/0000-0001-7848-076X, Pang, Jia Hao, Poole, Darren L., Tuttle, Tell ORCID logoORCID: https://orcid.org/0000-0003-2300-8921, Chiba, Shunsuke and Murphy, John A.;
CORE (COnnecting REpositories)