Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome

Nussbaumer, Martin G. and Bisig, Christoph and Bruns, Nico (2016) Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome. Chemical Communications, 52 (69). pp. 10537-10539. ISSN 1359-7345

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    Abstract

    The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl4. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.