VGLUT2 functions as a differential marker for hippocampal output neurons
Wozny, Christian and Beed, Prateep and Nitzan, Noam and Pössnecker, Yona and Rost, Benjamin R. and Schmitz, Dietmar (2018) VGLUT2 functions as a differential marker for hippocampal output neurons. Frontiers in Cellular Neuroscience, 12. 337. ISSN 1662-5102
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Official URL: https://doi.org/10.3389/fncel.2018.00337
Abstract
The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.
Creators(s): |
Wozny, Christian ![]() | Item type: | Article |
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ID code: | 65476 |
Keywords: | channelrhodopsin-2, entorhinal cortex, hippocampus, subiculum, synaptic transmission, VGLUT2, Neuroscience. Biological psychiatry. Neuropsychiatry, Pharmacy and materia medica, Cellular and Molecular Neuroscience |
Subjects: | Medicine > Internal medicine > Neuroscience. Biological psychiatry. Neuropsychiatry Medicine > Pharmacy and materia medica |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 19 Sep 2018 08:43 |
Last modified: | 21 Jan 2021 10:25 |
URI: | https://strathprints.strath.ac.uk/id/eprint/65476 |
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