VGLUT2 functions as a differential marker for hippocampal output neurons

Wozny, Christian and Beed, Prateep and Nitzan, Noam and Pössnecker, Yona and Rost, Benjamin R. and Schmitz, Dietmar (2018) VGLUT2 functions as a differential marker for hippocampal output neurons. Frontiers in Cellular Neuroscience, 12. 337. ISSN 1662-5102

[img]
Preview
 Text (Wozny-etal-FCN-2018-VGLUT2-functions-as-a-differential-marker-for-hippocampal)
Wozny_etal_FCN_2018_VGLUT2_functions_as_a_differential_marker_for_hippocampal.pdf
Final Published Version
License: Creative Commons Attribution 4.0 logo
Download (1MB)| Preview

    Abstract

    The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.

    Creators(s): Wozny, Christian ORCID logoORCID: https://orcid.org/0000-0003-4220-2033, Beed, Prateep, Nitzan, Noam, Pössnecker, Yona, Rost, Benjamin R. and Schmitz, Dietmar;
    Item type:Article
    ID code:65476
    Keywords:channelrhodopsin-2, entorhinal cortex, hippocampus, subiculum, synaptic transmission, VGLUT2, Neuroscience. Biological psychiatry. Neuropsychiatry, Pharmacy and materia medica, Cellular and Molecular Neuroscience
    Subjects:Medicine > Internal medicine > Neuroscience. Biological psychiatry. Neuropsychiatry
    Medicine > Pharmacy and materia medica
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:19 Sep 2018 08:43
    Last modified:02 Sep 2020 04:06
    URI:https://strathprints.strath.ac.uk/id/eprint/65476
    Export data:
    CORE (COnnecting REpositories)