VGLUT2 functions as a differential marker for hippocampal output neurons

Wozny, Christian and Beed, Prateep and Nitzan, Noam and Pössnecker, Yona and Rost, Benjamin R. and Schmitz, Dietmar (2018) VGLUT2 functions as a differential marker for hippocampal output neurons. Frontiers in Cellular Neuroscience, 12. 337. ISSN 1662-5102

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    Abstract

    The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.

    ORCID iDs

    Wozny, Christian ORCID logoORCID: https://orcid.org/0000-0003-4220-2033, Beed, Prateep, Nitzan, Noam, Pössnecker, Yona, Rost, Benjamin R. and Schmitz, Dietmar;
    CORE (COnnecting REpositories)