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SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

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Cognitive appraisals mediate affective reactivity in affiliative extraversion

Inglis, Greig and Obonsawin, Marc C. and Hunter, Simon C. (2018) Cognitive appraisals mediate affective reactivity in affiliative extraversion. Frontiers in Psychology, 9. ISSN 1664-1078

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    Extraversion is comprised of two main components of affiliation and agency. Affiliative and agentic extraversion have been found to predict positive activation in response to appetitive stimuli, and affiliative extraversion also predicts warmth-affection in response to affiliative stimuli. The aim of this study was to test whether cognitive appraisals could account for these personality-emotion relationships. In an online experiment, 192 participants completed affiliative and appetitive imagery tasks, and reported their affect before and after each task. Participants also reported on how they appraised the imagined events. Affiliative extraversion was positively associated with warmth-affection following the affiliative imagery, and this relationship was mediated by appraisals of intrinsic pleasantness and compatibility with internal standards. Affiliative extraversion also predicted positive activation following the affiliative imagery, and this relationship was mediated by appraisals of importance. Neither agentic nor affiliative extraversion predicted any other form of affect following either the affiliative or appetitive imagery tasks. These results suggest that cognitive appraisals may be one mechanism that mediate affective reactivity in affiliative extraversion, although future confirmatory studies are required to further test this hypothesis.