Oxidative addition of aryl electrophiles to a prototypical nickel(0) complex : mechanism and structure/reactivity relationships

Bajo, Sonia and Laidlaw, Gillian and Kennedy, Alan R. and Sproules, Stephen and Nelson, David J. (2017) Oxidative addition of aryl electrophiles to a prototypical nickel(0) complex : mechanism and structure/reactivity relationships. Organometallics, 36 (8). pp. 1662-1672. ISSN 0276-7333

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    Abstract

    Detailed kinetic studies of the reaction of a model Ni0 complex with a range of aryl electrophiles have been conducted. The reactions proceed via a fast ligand exchange pre-equilibrium, followed by oxidative addition to produce either [NiIX(dppf)] (and biaryl) or [NiII(Ar)X(dppf)]; the ortho substituent of the aryl halide determines selectivity between these possibilities. A reactivity scale is presented in which a range of substrates is quantitatively ranked in order of the rate at which they undergo oxidative addition. The rate of oxidative addition is loosely correlated to conversion in prototypical cross-coupling reactions. Substrates that lead to NiI products in kinetic experiments produce more homocoupling products under catalytic conditions.

    ORCID iDs

    Bajo, Sonia ORCID logoORCID: https://orcid.org/0000-0003-4803-566X, Laidlaw, Gillian, Kennedy, Alan R. ORCID logoORCID: https://orcid.org/0000-0003-3652-6015, Sproules, Stephen and Nelson, David J. ORCID logoORCID: https://orcid.org/0000-0002-9461-5182;
    • Item type:Article
      ID code:60367
      Dates:
      Date
      Event
      24 April 2017
      Published
      6 April 2017
      Published Online
      29 March 2017
      Accepted
      Notes:Copyright © 2017 American Chemical Society. Bajo, S., Laidlaw, G., Kennedy, A. R., Sproules, S., & Nelson, D. J. (2017). Oxidative addition of aryl electrophiles to a prototypical nickel(0) complex: mechanism and structure/reactivity relationships. Organometallics, 1-33. Article accepted for publication by ACS.
      Keywords:nickel, oxidative addition, mechanistic studies, kinetics, cross coupling, Chemistry, Metals and Alloys, Materials Chemistry, Chemistry (miscellaneous)
      Subjects:Science > Chemistry
      Department:Faculty of Science > Pure and Applied Chemistry
      Depositing user: Pure Administrator
      Date deposited:30 Mar 2017 09:30
      Last modified:23 Sep 2021 06:08
      Related URLs:
      URI:https://strathprints.strath.ac.uk/id/eprint/60367
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