Transforming LiTMP lithiation of challenging diazines via gallium alkyl trans-metal-trapping
Uzelac, Marina and Kennedy, Alan R. and Hevia, Eva and Mulvey, Robert E. (2016) Transforming LiTMP lithiation of challenging diazines via gallium alkyl trans-metal-trapping. Angewandte Chemie International Edition, 55. pp. 13147-13150. ISSN 1433-7851
|
Text (Uzelac-etal-AC-2016-Transforming-LiTMP-lithiation-of-challenging-diazines-via-gallium-alkyl-trans-metal-trapping)
Uzelac_etal_AC_2016_Transforming_LiTMP_lithiation_of_challenging_diazines_via_gallium_alkyl_trans_metal_trapping.pdf Final Published Version License: ![]() Download (1MB)| Preview |
Abstract
This study establishes a new trans-metal-trapping (TMT) protocol based on a mixture of LiTMP (the base) and tris(trimethylsilylmethyl)gallium [Ga(CH2SiMe3)3, GaR3] (the trap) that, operating in a tandem manner, is effective for the regioselective deprotonation of sensitive diazines in hydrocarbon solution as illustrated through reactions of pyrazine, pyridazine and pyrimidine, as well as through the N-S heterocycle benzothiazole, the metallo-activated complexes of all of which have been isolated and structurally defined.
Creators(s): |
Uzelac, Marina ![]() ![]() ![]() ![]() | Item type: | Article |
---|---|
ID code: | 57758 |
Notes: | This is the peer reviewed version of the following article: Transforming LiTMP lithiation of challenging diazines via gallium alkyl trans-metal-trapping. / Uzelac, Marina; Kennedy, Alan R.; Hevia, Eva; Mulvey, Robert E. In: Angewandte Chemie International Edition, 06.09.2016., which has been published in final form at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
Keywords: | trans-metal-trapping, TMT, sensitive diazines, LiTMP lithiation, Physical and theoretical chemistry, Physical and Theoretical Chemistry |
Subjects: | Science > Chemistry > Physical and theoretical chemistry |
Department: | Faculty of Science > Pure and Applied Chemistry |
Depositing user: | Pure Administrator |
Date deposited: | 12 Sep 2016 11:41 |
Last modified: | 05 Mar 2021 03:34 |
Related URLs: | |
URI: | https://strathprints.strath.ac.uk/id/eprint/57758 |
Export data: |