Static mode microfluidic cantilevers for detection of waterborne pathogens

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Bridle, Helen and Wang, Wenxing and Gavriilidou, Despoina and Amalou, Farid and Hand, Duncan P. and Shu, Wenmiao (2016) Static mode microfluidic cantilevers for detection of waterborne pathogens. Sensors and Actuators A: Physical, 247. pp. 144-149. ISSN 0924-4247 (https://doi.org/10.1016/j.sna.2016.05.011)

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Abstract

This paper reports on the first demonstration of polymeric microfluidic cantilever sensors. Microcantilever sensors, magnetic beads, and microfluidic technology have been combined to create a polymer based biosensor. Using cheap materials like polyimide, a simple fabrication method has been developed to produce cantilevers with an embedded microfluidic channel. The advantage of this approach is that the addition of a microfluidic channel enables the analysis of smaller volumes and increases the capture efficiency in applications detecting rare analytes. As a proof of principle the system has been applied for the detection of the waterborne protozoan parasite Cryptosporidium, achieving sensitivity comparable to QCM, whereas a previous set-up without the microfluidic channel was unable to detect the parasite.

ORCID iDs

Bridle, Helen, Wang, Wenxing, Gavriilidou, Despoina, Amalou, Farid, Hand, Duncan P. and Shu, Wenmiao ORCID logoORCID: https://orcid.org/0000-0002-1220-361X;
CORE (COnnecting REpositories)