Picture of mobile phone running fintech app

Fintech: Open Access research exploring new frontiers in financial technology

Strathprints makes available Open Access scholarly outputs by the Department of Accounting & Finance at Strathclyde. Particular research specialisms include financial risk management and investment strategies.

The Department also hosts the Centre for Financial Regulation and Innovation (CeFRI), demonstrating research expertise in fintech and capital markets. It also aims to provide a strategic link between academia, policy-makers, regulators and other financial industry participants.

Explore all Strathclyde Open Access research...

Electrochemiluminescent detection of methamphetamine and amphetamine

McGeehan, Jonathan and Dennany, Lynn (2016) Electrochemiluminescent detection of methamphetamine and amphetamine. Forensic Science International, 264. pp. 1-6. ISSN 0379-0738

[img]
Preview
Text (McGeehan-Dennany-FSI2016-electrochemiluminescent-detection-methamphetamine)
McGeehan_Dennany_FSI2016_electrochemiluminescent_detection_methamphetamine.pdf
Accepted Author Manuscript
License: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 logo

Download (926kB) | Preview

Abstract

Direct detection of amphetamine type stimulants (ATS) including methylamphetamine (MA) in street samples and biological matrices without the need for pretreatment or extraction is a great challenge for forensic drug analysis. Electrochemical techniques, such as electrochemiluminescence (ECL), are promising tools for this area of analysis. This contribution focuses on the electrochemical and photochemical properties of [Ru(bpy)3]2+ nafion composite films and their subsequent use for the detection of ATS in particular MA. Under optimised conditions, the response linearly increased with the concentration over the concentration range 50 pM <[MA]< 1 mM while an equivalent dynamic range was obtained for amphetamine with a correlation coefficient of 0.9903 and 0.9948 respectively. The ECL signal was monitored at ~620 nm, representing the λmax for the [Ru(bpy)3]2+ nafion composite films. This wavelength is shifted by approximately 15 nm compared to the photoexcited λmax for the same system. The modified films were formed by direct interaction with the electrode surface without the need for surface modification or chain linkers. This is a major advantage for the fabrication of any sensor as it reduces the synthesis times resulting in more economically and cheaper production costs. This technique is simple, rapid, selective and sensitive, and shows potential for the high-throughput quantitation of ATS as well as possibilities for adaptation with other techniques such as FIA or LC systems.