Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers

Sandison, M E and Morgan, H (2005) Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers. Journal of Micromechanics and Microengineering, 15 (7). S139-S144. ISSN 0960-1317

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Official URL: https://doi.org/10.1088/0960-1317/15/7/020

Abstract

A polymer microfluidic device has been fabricated using rapid prototyping techniques. The device was built to allow the formation and subsequent investigation of artificial bilayer lipid membranes (BLMs). A simple dry film photoresist stamp was used to hot emboss microfluidic channels into PMMA films. Laser micromachining was employed to form an aperture through the PMMA channels, across which the BLM was later formed. The dry film photoresist was also used as a simple etch mask for the deep etching of glass substrates in buffered HF solutions, which was used in this work for the production of glass embossing stamps. We show that bilayer films can be successfully produced across laser micromachined apertures in PMMA films.

Creators(s):	Sandison, M E ORCID: https://orcid.org/0000-0003-1021-1461 and Morgan, H;
Item type:	Article
ID code:	54421
Keywords:	polymer microfluidic devices, bilayer lipid membranes, laser micromachining, microfabrication, Bioengineering, Computational Mechanics, Mechanics of Materials, Materials Science(all), Instrumentation
Subjects:	Technology > Engineering (General). Civil engineering (General) > Bioengineering
Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Engineering > Biomedical Engineering
Depositing user:	Pure Administrator
Date deposited:	01 Oct 2015 13:00
Last modified:	06 Jan 2021 08:37
Related URLs:	Scopus publication
URI:	https://strathprints.strath.ac.uk/id/eprint/54421
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