Rapid genotyping of Shigella sonnei using multiplex high resolution melting

Mazi, Waleed and Sangal, Vartul and Saeed, Amir and Sandstom, Gunnar and Weill, François-Xavier and Yu, Jun (2015) Rapid genotyping of Shigella sonnei using multiplex high resolution melting. Journal of Clinical Microbiology, 53 (7). pp. 1-2. ISSN 0095-1137

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Abstract

Shigella sonnei, an emerging global cause of shigellosis, consists of four distinct lineages and the current pandemic involves several geographically associated, multidrug- resistant clones that belong to lineage III (1-3). A typing scheme based on high resolution melting (HRM) of six chromosomal single nucleotide polymorphisms (SNPs) has been described to identify all lineages/sub-lineages (4).