Vibrational spectroscopic methods for cytology and cellular research

Clemens, Graeme and Hands, James R. and Dorling, Konrad M. and Baker, Matthew J. (2014) Vibrational spectroscopic methods for cytology and cellular research. Analyst, 139 (18). pp. 4411-4444. ISSN 0003-2654

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Official URL: https://doi.org/10.1039/c4an00636d

Abstract

The use of vibrational spectroscopy, FTIR and Raman, for cytology and cellular research has the potential to revolutionise the approach to cellular analysis. Vibrational spectroscopy is non-destructive, simple to operate and provides direct information. Importantly it does not require expensive exogenous labels that may affect the chemistry of the cell under analysis. In addition, the advent of spectroscopic microscopes provides the ability to image cells and acquire spectra with a subcellular resolution. This introductory review focuses on recent developments within this fast paced field and highlights potential for the future use of FTIR and Raman spectroscopy. We particularly focus on the development of live cell research and the new technologies and methodologies that have enabled this.

Author(s):	Clemens, Graeme, Hands, James R., Dorling, Konrad M. and Baker, Matthew J. ORCID: https://orcid.org/0000-0003-2362-8581
Item type:	Article
ID code:	50095
Keywords:	vibrational spectroscopy, cytology, cellular research, Chemistry, Analytical Chemistry, Spectroscopy, Electrochemistry, Biochemistry, Environmental Chemistry
Subjects:	Science > Chemistry
Department:	Faculty of Science > Pure and Applied Chemistry
Depositing user:	Pure Administrator
Date deposited:	03 Nov 2014 11:38
Last modified:	08 Nov 2019 06:08
Related URLs:	Scopus publication
URI:	https://strathprints.strath.ac.uk/id/eprint/50095
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