Vibrational spectroscopic methods for cytology and cellular research

Clemens, Graeme and Hands, James R. and Dorling, Konrad M. and Baker, Matthew J. (2014) Vibrational spectroscopic methods for cytology and cellular research. Analyst, 139 (18). pp. 4411-4444. ISSN 0003-2654

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Abstract

The use of vibrational spectroscopy, FTIR and Raman, for cytology and cellular research has the potential to revolutionise the approach to cellular analysis. Vibrational spectroscopy is non-destructive, simple to operate and provides direct information. Importantly it does not require expensive exogenous labels that may affect the chemistry of the cell under analysis. In addition, the advent of spectroscopic microscopes provides the ability to image cells and acquire spectra with a subcellular resolution. This introductory review focuses on recent developments within this fast paced field and highlights potential for the future use of FTIR and Raman spectroscopy. We particularly focus on the development of live cell research and the new technologies and methodologies that have enabled this.

ORCID iDs

Clemens, Graeme, Hands, James R., Dorling, Konrad M. and Baker, Matthew J. ORCID logoORCID: https://orcid.org/0000-0003-2362-8581;
  • Item type:Article
    ID code:50095
    Dates:
    Date
    Event
    21 September 2014
    Published
    27 June 2014
    Published Online
    27 June 2014
    Accepted
    Keywords:vibrational spectroscopy, cytology, cellular research, Chemistry, Analytical Chemistry, Spectroscopy, Electrochemistry, Biochemistry, Environmental Chemistry
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:03 Nov 2014 11:38
    Last modified:30 Apr 2021 02:04
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/50095
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