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Rocaglamides, glycosides, and putrescine bisamides from Aglaia dasyclada

Lin, W. H. and Ebel, Rainer and Edrada-Ebel, Ruangelie and Wray, Victor and Nimtz, Manfred and Sumaryono, W and Proksch, Peter (2001) Rocaglamides, glycosides, and putrescine bisamides from Aglaia dasyclada. Journal of Natural Products, 64 (9). pp. 1216-1220. ISSN 0163-3864

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Abstract

A phytochemical analysis of the leaves of Aglaia dasyclada collected in Yunnan Province (People's Republic of China) yielded five cyclopentabenzofurans (1-5) of the rocaglamide family that are common secondary metabolites of Aglaia species as well as four biogenetically related compounds of the aglain (7), aglaforbesin (8) and forbaglin (9, 10) types. In addition, the cinnamic acid amide dasyclamide (6), which is a putative biogenetic precursor of these compounds (7-10), was isolated. The structures of the new compounds (6-10) were assigned unambiguously from the combined use of 1D and 2D NMR spectroscopy and mass spectrometry.