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Aglacins I-K, three highly methoxylated lignans from Aglaia cordata

Wang, Bin-Gui and Ebel, Rainer and Wang, Chang-Yun and Edrada, Ru Angelie and Wray, Victor and Proksch, Peter and Edrada-Ebel, Ruangelie (2004) Aglacins I-K, three highly methoxylated lignans from Aglaia cordata. Journal of Natural Products, 67 (4). pp. 682-684. ISSN 0163-3864

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Further chemical investigation of the stem bark of Aglaia cordata has led to the isolation and identification of three new lignans, namely, aglacins I-K (1-3), all of which contain two contiguous trimethoxylated phenyl systems. Among them, aglacins I and J (1 and 2) are new members of the aryltetralin cyclic lactol class, while aglacin K (3) is a new example of tetrahydrofuran lignan. The structures of these compounds were established on the basis of spectroscopic data interpretation.