Picture water droplets

Developing mathematical theories of the physical world: Open Access research on fluid dynamics from Strathclyde

Strathprints makes available Open Access scholarly outputs by Strathclyde's Department of Mathematics & Statistics, where continuum mechanics and industrial mathematics is a specialism. Such research seeks to understand fluid dynamics, among many other related areas such as liquid crystals and droplet evaporation.

The Department of Mathematics & Statistics also demonstrates expertise in population modelling & epidemiology, stochastic analysis, applied analysis and scientific computing. Access world leading mathematical and statistical Open Access research!

Explore all Strathclyde Open Access research...

Kahalalide derivatives from the Indian sacoglossan mollusk Elysia grandifolia

Ashour, Mohamed and Edrada, RuAngelie and Ebel, Rainer and Wray, Victor and Wätjen, Wim and Padmakumar, K and Müller, Werner E G and Lin, Wen Han and Proksch, Peter and Edrada-Ebel, Ruangelie (2006) Kahalalide derivatives from the Indian sacoglossan mollusk Elysia grandifolia. Journal of Natural Products, 69 (11). pp. 1547-1553. ISSN 0163-3864

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

Two new cyclic depsipeptide derivatives, kahalalides R (1) and S (2), together with two known congeners, kahalalides F (3) and D (4), were isolated from the Indian sacoglossan mollusk Elysia grandifolia. The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, HMBC) and mass spectrometric (FABMS, ESIMS, MALDI-TOF/PSD) data, which also included Marfey amino acid analyses. The new derivative kahalalide R was found to exert comparable or even higher cytotoxicity than the potential drug candidate kahalalide F toward the MCF7 human mammary carcinoma cell line.