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Simulating drug-eluting stents : progress made and the way forward

McGinty, Sean and McCormick, Christopher and McKee, Sean and Wheel, Marcus and Kennedy, Simon and Oldroyd, Keith G. (2013) Simulating drug-eluting stents : progress made and the way forward. In: Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), 2013-07-29 - 2013-07-31.

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Abstract

Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary interventions. Drug-eluting stents have been around for over a decade, and while progress is continually being made, they are not suitable in all patients and lesion types. Furthermore there are still real concerns over incomplete healing and late stent thrombosis. In this paper, some modelling approaches are reviewed and the future of modelling and simulation in this field is discussed.