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Literary linguistics: Open Access research in English language

Strathprints makes available Open Access scholarly outputs by English Studies at Strathclyde. Particular research specialisms include literary linguistics, the study of literary texts using techniques drawn from linguistics and cognitive science.

The team also demonstrates research expertise in Renaissance studies, researching Renaissance literature, the history of ideas and language and cultural history. English hosts the Centre for Literature, Culture & Place which explores literature and its relationships with geography, space, landscape, travel, architecture, and the environment.

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Vaccination against Toxoplasmosis : current status and future prospects

Roberts, Craig and McLeod, Rima and Henriquez, Fiona and Alexander, James (2013) Vaccination against Toxoplasmosis : current status and future prospects. In: Toxoplasma Gondii. PERGAMON-ELSEVIER SCIENCE LTD, London, 995–1045. ISBN 9780123964816

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Abstract

A vaccine capable of protecting against Toxoplasma gondii would have both beneficial medical and veterinary impacts. Successful vaccination of humans would not only reduce mortality and morbidity, but also reduce the financial burden of lifelong care required by those worst affected. A veterinary vaccine would have the dual advantages of increasing livestock productivity while reducing the public health risk associated with eating contaminated meat. Herein we review progress towards these goals using both large animal studies and the murine models of disease. Early approaches were largely empirical and used attenuated organisms, parasite extracts, or defined sub-units based upon the limited genomic data previously available. The recent elucidation of the T. gondii genome, understanding of T. gondii population structures, predicative algorithms for MHC binding peptides, facile manipulation of T. gondii taken together with a wealth of immunological knowledge should significantly promote new vaccine development.