Picture of UK Houses of Parliament

Leading national thinking on politics, government & public policy through Open Access research

Strathprints makes available scholarly Open Access content by researchers in the School of Government & Public Policy, based within the Faculty of Humanities & Social Sciences.

Research here is 1st in Scotland for research intensity and spans a wide range of domains. The Department of Politics demonstrates expertise in understanding parties, elections and public opinion, with additional emphases on political economy, institutions and international relations. This international angle is reflected in the European Policies Research Centre (EPRC) which conducts comparative research on public policy. Meanwhile, the Centre for Energy Policy provides independent expertise on energy, working across multidisciplinary groups to shape policy for a low carbon economy.

Explore the Open Access research of the School of Government & Public Policy. Or explore all of Strathclyde's Open Access research...

Ophiobolin sesterterpenoids and pyrrolidine alkaloids from the sponge-derived fungus aspergillus ustus

Liu, H. B. and Edrada-Ebel, R. and Ebel, R. and Wang, Y. and Schulz, B. and Draeger, S. and Muller, W. E. G. and Wray, V. and Lin, W. H. and Proksch, P. (2011) Ophiobolin sesterterpenoids and pyrrolidine alkaloids from the sponge-derived fungus aspergillus ustus. Helvetica Chimica Acta, 94 (4). pp. 623-631. ISSN 0018-019X

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

Chemical examination of the fungus Aspergillus ustus isolated from the Mediterranean sponge Suberites domuncula yielded the five new ophiobolin-type sesterterpenoids 1–5 and the two new pyrrolidine alkaloids 6 and 7, together with the known compound aurantiamine and cerebroside D. The structures of the new compounds were unambiguously elucidated on the basis of extensive spectroscopic-data analysis (1D- and 2D-NMR, MS, and UV) and comparison with literature data. All compounds were evaluated for their cytotoxicity against murine lymphoma cell line L5178Y.